The Frontiersmen (Narratives of America series, Book 1)

Driven from their homeland, the Indians fought bitterly to keep a final stronghold east of the Mississippi.  Savage cunning, strength, skill, and knowledge of the wilderness were their weapons, and the Indians used them mercilessly.  But they couldn't foresee the white men who would come later, men who loved the land as much as they did, who wanted it for their own.  Men who learned the Indian tricks and matched brutality for brutality.